Tip
Pyke will have a hard time initiating combat if you chip away his health through [R]-[Q] pokes. However, always keep in mind that Pyke’s (Q) or (E) can be lethal. Use the bonus movement speed on [E] to disengage.
Karma vs Pyke

Pyke will have a hard time initiating combat if you chip away his health through [R]-[Q] pokes. However, always keep in mind that Pyke’s (Q) or (E) can be lethal. Use the bonus movement speed on [E] to disengage.